As a total eclipse casts its shadow across the globe, a genetics professor in India is led by his father's disappearance to uncover a secret theory -- there are people with super powers living among us. A young dreamer tries to convince his politician brother that he can fly. A high school cheerleader learns that she is totally indestructible. A single mother struggles to make ends meet to support her young son and discovers that her mirror image has a secret. A gifted artist, whose drug addiction is destroying his life and relationship with his girlfriend, can paint the future. And in Japan, a young man develops a way to stop time through sheer will power. Yet, unbeknownst to them all, their ultimate destiny is nothing less than saving the world...

Outside a bizarre, gruesome crime scene, Los Angeles beat cop Matt Parkman is the only one who can hear the cries of a missing little girl. Claire almost reveals her secret ability to the entire school after learning that her injury attempt tape has disappeared. Thinking she's going crazy, Niki loses another block of time after waking to find some brutally murdered thugs in her garage, only to be confronted by Social Services about son Micah. While office drone Hiro investigates New York, Nathan confronts Peter following his plunge off a building.