Present Scarpetta and Marino uncover troubling similarities between their murder victim and the 'accidental' death of a jogger six months earlier; while in the past, Scarpetta suspects that someone from within her own office is attempting to sabotage her, and she makes a huge discovery in the case.

In the present, Scarpetta and Benton's marriage is put to the test when Kay is called in by the FBI to perform autopsies on two dead astronauts found at a crash site that might connect to the murder victim. In the past, it's Friday night and the killer could strike at any moment.

Past Scarpetta and Benton devise a risky plan to bait the serial killer out of hiding. In the present, Scarpetta orders the exhumation of the dead jogger's body, convinced that there's a connection between the jogger's death and the murder victim. At home, Kay and Benton's mounting secrets and lies come to a boiling point.

After confirming a connection between the two deaths in the present, Scarpetta faces mounting professional and personal crises. In the past, she makes a breakthrough in the case.

In the past, Scarpetta and Marino wrestle with the lie that bonds them forever. In the present, with her family, career, and marriage now fractured, Scarpetta finds herself all alone while a killer is still on the loose...